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5-HT(7) receptor-dependent intestinal neurite outgrowth contributes to visceral hypersensitivity in irritable bowel syndrome

Irritable bowel syndrome (IBS) is characterized by visceral hypersensitivity (VH) associated with abnormal serotonin/5-hydroxytryptamine (5-HT) metabolism and neurotrophin-dependent mucosal neurite outgrowth. The underlying mechanisms of VH remain poorly understood. We investigated the role of 5-HT(...

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Detalles Bibliográficos
Autores principales:	Chang, Wen-Ying, Yang, Yi-Ting, She, Meng-Ping, Tu, Chia-Hung, Lee, Tsung-Chun, Wu, Ming-Shiang, Sun, Chin-Hung, Hsin, Ling-Wei, Yu, Linda Chia-Hui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group US 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9420680/ https://www.ncbi.nlm.nih.gov/pubmed/35585132 http://dx.doi.org/10.1038/s41374-022-00800-z

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