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Endothelial PDGF-BB/PDGFR-β signaling promotes osteoarthritis by enhancing angiogenesis-dependent abnormal subchondral bone formation

The mechanisms that coordinate the shift from joint homeostasis to osteoarthritis (OA) remain unknown. No pharmacological intervention can currently prevent the progression of osteoarthritis. Accumulating evidence has shown that subchondral bone deterioration is a primary trigger for overlying carti...

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Detalles Bibliográficos
Autores principales: Cui, Zhuang, Wu, Hangtian, Xiao, Ye, Xu, Ting, Jia, Junjie, Lin, Hancheng, Lin, Rongmin, Chen, Kun, Lin, Yihuang, Li, Kaiqun, Wu, Xiaohu, Li, Changjun, Yu, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9420732/
https://www.ncbi.nlm.nih.gov/pubmed/36031625
http://dx.doi.org/10.1038/s41413-022-00229-6