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YAP9/A20 complex suppresses proinflammatory responses and provides novel anti-inflammatory therapeutic potentials

Innate anti-inflammatory mechanisms are essential for immune homeostasis and can present opportunities to intervene inflammatory diseases. In this report, we found that YAP isoform 9 (YAP9) is an essential negative regulator of the potent inflammatory stimuli such as TNFα, IL-1β, and LPS. YAP9 const...

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Detalles Bibliográficos
Autores principales: Yang, Fengyuan Mandy, Shen, Liya, Fan, Dengxia Denise, Bai, Yaqin, Li, Bizhou, Lee, Jongdae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9420849/
https://www.ncbi.nlm.nih.gov/pubmed/36045678
http://dx.doi.org/10.3389/fimmu.2022.914381