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Live functional assays reveal longitudinal maturation of transepithelial transport in kidney organoids

Kidney organoids derived from hPSCs have opened new opportunities to develop kidney models for preclinical studies and immunocompatible kidney tissues for regeneration. Organoids resemble native nephrons that consist of filtration units and tubules, yet little is known about the functional capacity...

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Detalles Bibliográficos
Autores principales: Rizki-Safitri, Astia, Gupta, Navin, Hiratsuka, Ken, Kobayashi, Kenichi, Zhang, Chengcheng, Ida, Kazumi, Satlin, Lisa M., Morizane, Ryuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9420851/
https://www.ncbi.nlm.nih.gov/pubmed/36046340
http://dx.doi.org/10.3389/fcell.2022.978888