Synthesis, bioactivity, and molecular docking of novel arylpiperazine derivatives as potential AR antagonists

Prostate cancer is one of the malignant tumors and the second most common malignant tumor in men. Clinically used androgen receptor (AR)–targeted drugs can antagonize androgen and inhibit tumor growth, but these drugs can cause serious resistance problems. To develop novel AR antagonists, 22 kinds o...

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Detalles Bibliográficos
Autores principales: Qi, Yueheng, Chen, Hong, Chen, Shijin, Shen, Jianliang, Li, Jingguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9420858/
https://www.ncbi.nlm.nih.gov/pubmed/36046733
http://dx.doi.org/10.3389/fchem.2022.947065

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9420858/
https://www.ncbi.nlm.nih.gov/pubmed/36046733
http://dx.doi.org/10.3389/fchem.2022.947065

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