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BAG6 negatively regulates the RLR signaling pathway by targeting VISA/MAVS

The virus-induced signaling adaptor protein VISA (also known as MAVS, ISP-1, Cardif) is a critical adaptor protein in the innate immune response to RNA virus infection. Upon viral infection, VISA self-aggregates to form a sizeable prion-like complex and recruits downstream signal components for sign...

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Detalles Bibliográficos
Autores principales: Huang, Jing-Ping, Li, Jing, Xiao, Yan-Ping, Xu, Liang-Guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9420869/
https://www.ncbi.nlm.nih.gov/pubmed/36045679
http://dx.doi.org/10.3389/fimmu.2022.972184