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BAG6 negatively regulates the RLR signaling pathway by targeting VISA/MAVS
The virus-induced signaling adaptor protein VISA (also known as MAVS, ISP-1, Cardif) is a critical adaptor protein in the innate immune response to RNA virus infection. Upon viral infection, VISA self-aggregates to form a sizeable prion-like complex and recruits downstream signal components for sign...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9420869/ https://www.ncbi.nlm.nih.gov/pubmed/36045679 http://dx.doi.org/10.3389/fimmu.2022.972184 |