Exosomes derived from human umbilical cord mesenchymal stem cells protect against papain-induced emphysema by preventing apoptosis through activating VEGF-VEGFR2-mediated AKT and MEK/ERK pathways in rats

INTRODUCTION: Chronic obstructive pulmonary disease (COPD) is a leading cause of high mortality and heavy burden in the world. Unfortunately, emphysema, as an important component of COPD, has no curative treatments currently. Recently, human umbilical cord mesenchymal stem cells-derived exosomes (hU...

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Detalles Bibliográficos
Autores principales: Chen, Qin, Lin, Jiang, Deng, Zhaoqun, Qian, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society for Regenerative Medicine 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9420880/
https://www.ncbi.nlm.nih.gov/pubmed/36092502
http://dx.doi.org/10.1016/j.reth.2022.07.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9420880/
https://www.ncbi.nlm.nih.gov/pubmed/36092502
http://dx.doi.org/10.1016/j.reth.2022.07.002

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