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Production of human entorhinal stellate cell-like cells by forward programming shows an important role of Foxp1 in reprogramming

Stellate cells are principal neurons in the entorhinal cortex that contribute to spatial processing. They also play a role in the context of Alzheimer’s disease as they accumulate Amyloid beta early in the disease. Producing human stellate cells from pluripotent stem cells would allow researchers to...

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Detalles Bibliográficos
Autores principales: Bergmann, Tobias, Liu, Yong, Skov, Jonathan, Mogus, Leo, Lee, Julie, Pfisterer, Ulrich, Handfield, Louis-Francois, Asenjo-Martinez, Andrea, Lisa-Vargas, Irene, Seemann, Stefan E., Lee, Jimmy Tsz Hang, Patikas, Nikolaos, Kornum, Birgitte Rahbek, Denham, Mark, Hyttel, Poul, Witter, Menno P., Gorodkin, Jan, Pers, Tune H., Hemberg, Martin, Khodosevich, Konstantin, Hall, Vanessa Jane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9420913/
https://www.ncbi.nlm.nih.gov/pubmed/36046338
http://dx.doi.org/10.3389/fcell.2022.976549