Finasteride Alleviates High Fat Associated Protein-Overload Nephropathy by Inhibiting Trimethylamine N-Oxide Synthesis and Regulating Gut Microbiota

Unhealthy diet especially high-fat diet (HFD) is the major cause of hyperlipidemia leading to deterioration of chronic kidney diseases (CKD) in patients. Trimethylamine N-oxide (TMAO) is a gut-derived uremic toxin. Our previous clinical study demonstrated that the elevation of TMAO was positively co...

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Detalles Bibliográficos
Autores principales: Wang, Zuoyuan, You, Li, Ren, Yuan, Zhu, Xiaoye, Mao, Xiaoyi, Liang, Xiaowan, Wang, Tingting, Guo, Yumeng, Liu, Te, Xue, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9420981/
https://www.ncbi.nlm.nih.gov/pubmed/36045744
http://dx.doi.org/10.3389/fphys.2022.900961

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9420981/
https://www.ncbi.nlm.nih.gov/pubmed/36045744
http://dx.doi.org/10.3389/fphys.2022.900961

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