Pharmacological inhibition of SMYD2 protects against cisplatin-induced acute kidney injury in mice

The histone methyltransferase SET and MYND domain protein 2 (SMYD2) has been implicated in tumorigenesis through methylating histone H3 at lysine36 (H3K36) and some non-histone substrates. Currently, the role of SMYD2 in acute kidney injury (AKI) remains unknown. Here, we investigated the effects of...

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Detalles Bibliográficos
Autores principales: Cui, Binbin, Hou, Xiying, Liu, Mengjun, Li, Qing, Yu, Chao, Zhang, Shenglei, Wang, Yi, Wang, Jun, Zhuang, Shougang, Liu, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9421052/
https://www.ncbi.nlm.nih.gov/pubmed/36046818
http://dx.doi.org/10.3389/fphar.2022.829630

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9421052/
https://www.ncbi.nlm.nih.gov/pubmed/36046818
http://dx.doi.org/10.3389/fphar.2022.829630

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