Cargando…

Obtaining protein foldability information from computational models of AlphaFold2 and RoseTTAFold

The recent breakthrough from AlphaFold2 and RoseTTAFold set a profound milestone for solving the protein folding problem, but they were not explicitly trained to predict protein foldability, i.e., if a protein can really fold into the predicted 3D structure. We wondered if the computational models f...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Sen, Wu, Kan, Chen, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9421090/
https://www.ncbi.nlm.nih.gov/pubmed/36051869
http://dx.doi.org/10.1016/j.csbj.2022.08.034