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Loganin attenuates interleukin-1β-induced chondrocyte inflammation, cartilage degeneration, and rat synovial inflammation by regulating TLR4/MyD88/NF-κB

OBJECTIVE: Inflammation plays a crucial part in osteoarthritis (OA) development. This work aimed to explore loganin’s role and molecular mechanism in inflammation and clarify its anti-inflammatory effects in OA treatment. METHODS: Chondrocytes were stimulated using interleukin (IL)-1β and loganin at...

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Detalles Bibliográficos
Autores principales: Wan, Haishan, Li, Chaoyi, Yang, Yi, Chen, Dingzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9421229/
https://www.ncbi.nlm.nih.gov/pubmed/36000146
http://dx.doi.org/10.1177/03000605221104764