Cargando…
Loganin attenuates interleukin-1β-induced chondrocyte inflammation, cartilage degeneration, and rat synovial inflammation by regulating TLR4/MyD88/NF-κB
OBJECTIVE: Inflammation plays a crucial part in osteoarthritis (OA) development. This work aimed to explore loganin’s role and molecular mechanism in inflammation and clarify its anti-inflammatory effects in OA treatment. METHODS: Chondrocytes were stimulated using interleukin (IL)-1β and loganin at...
Autores principales: | Wan, Haishan, Li, Chaoyi, Yang, Yi, Chen, Dingzhong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9421229/ https://www.ncbi.nlm.nih.gov/pubmed/36000146 http://dx.doi.org/10.1177/03000605221104764 |
Ejemplares similares
-
Soyasaponins reduce inflammation by downregulating MyD88 expression and suppressing the recruitments of TLR4 and MyD88 into lipid rafts
por: Chen, Junbin, et al.
Publicado: (2020) -
Schisandrin B Attenuates Diabetic Cardiomyopathy by Targeting MyD88 and Inhibiting MyD88‐Dependent Inflammation
por: Luo, Wu, et al.
Publicado: (2022) -
Selective disruption of TLR2-MyD88 interaction inhibits inflammation and attenuates Alzheimer’s pathology
por: Rangasamy, Suresh B., et al.
Publicado: (2018) -
Mucus clearance, MyD88-dependent and MyD88-independent immunity modulate lung susceptibility to spontaneous bacterial infection and inflammation
por: Livraghi-Butrico, Alessandra, et al.
Publicado: (2012) -
TLR4/MyD88 -mediated CCL2 production by lipopolysaccharide (endotoxin): Implications for metabolic inflammation
por: Akhter, Nadeem, et al.
Publicado: (2018)