The Anticancer Effects of the Pro-Apoptotic Benzofuran-Isatin Conjugate (5a) Are Associated With p53 Upregulation and Enhancement of Conventional Chemotherapeutic Drug Efficiency in Colorectal Cancer Cell Lines

The present study aimed to investigate in-depth a cytotoxic novel benzofuran-isatin conjugate (5a, 3-methyl-N'-(2-oxoindolin-3-ylidene)benzofuran-2-carbohydrazide) with promising potential anticancer activities in colorectal adenocarcinoma HT29 and metastatic colorectal cancer (CRC) SW620 cell...

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Detalles Bibliográficos
Autores principales: Vaali-Mohammed, Mansoor-Ali, Abdulla, Maha-Hamadien, Matou-Nasri, Sabine, Eldehna, Wagdy M., Meeramaideen, M., Elkaeed, Eslam B., El-Watidy, Mohammed, Alhassan, Noura S., Alkhaya, Khayal, Al Obeed, Omar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9421242/
https://www.ncbi.nlm.nih.gov/pubmed/36046830
http://dx.doi.org/10.3389/fphar.2022.923398

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9421242/
https://www.ncbi.nlm.nih.gov/pubmed/36046830
http://dx.doi.org/10.3389/fphar.2022.923398

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