Differential regulation of alternate promoter regions in Sox17 during endodermal and vascular endothelial development

Sox17 gene expression is essential for both endothelial and endodermal cell differentiation. To better understand the genetic basis for the expression of multiple Sox17 mRNA forms, we identified and performed CRISPR/Cas9 mutagenesis of two evolutionarily conserved promoter regions (CRs). The deletio...

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Detalles Bibliográficos
Autores principales: Trinh, Linh T., Osipovich, Anna B., Sampson, Leesa, Wong, Jonathan, Wright, Chris V.E., Magnuson, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9421400/
https://www.ncbi.nlm.nih.gov/pubmed/36046192
http://dx.doi.org/10.1016/j.isci.2022.104905

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9421400/
https://www.ncbi.nlm.nih.gov/pubmed/36046192
http://dx.doi.org/10.1016/j.isci.2022.104905

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