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Differential regulation of alternate promoter regions in Sox17 during endodermal and vascular endothelial development
Sox17 gene expression is essential for both endothelial and endodermal cell differentiation. To better understand the genetic basis for the expression of multiple Sox17 mRNA forms, we identified and performed CRISPR/Cas9 mutagenesis of two evolutionarily conserved promoter regions (CRs). The deletio...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9421400/ https://www.ncbi.nlm.nih.gov/pubmed/36046192 http://dx.doi.org/10.1016/j.isci.2022.104905 |