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Motor cortical patterns of upper motor neuron pathology in amyotrophic lateral sclerosis: A 3 T MRI study with iron-sensitive sequences

BACKGROUND: Patterns of initiation and propagation of disease in Amyotrophic Lateral Sclerosis (ALS) are still partly unknown. Single or multiple foci of neurodegeneration followed by disease diffusion to contiguous or connected regions have been proposed as mechanisms underlying symptom occurrence....

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Detalles Bibliográficos
Autores principales: Donatelli, Graziella, Costagli, Mauro, Cecchi, Paolo, Migaleddu, Gianmichele, Bianchi, Francesca, Frumento, Paolo, Siciliano, Gabriele, Cosottini, Mirco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9421531/
https://www.ncbi.nlm.nih.gov/pubmed/36002961
http://dx.doi.org/10.1016/j.nicl.2022.103138