Elevated Protein Kinase A Activity in Stomach Mesenchyme Disrupts Mesenchymal-epithelial Crosstalk and Induces Preneoplasia

BACKGROUND & AIMS: Mesenchymal-epithelial crosstalk (MEC) in the stomach is executed by pathways such as bone morphogenetic protein (BMP) and extracellular signal-regulated kinase (ERK). Mis-regulation of MEC disrupts gastric homeostasis and causes tumorigenesis. Protein Kinase A (PKA) crosstalk...

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Detalles Bibliográficos
Autores principales: Puri, Pawan, Grimmett, Garfield, Faraj, Rawah, Gibson, Laurielle, Gilbreath, Ebony, Yoder, Bradley K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9421585/
https://www.ncbi.nlm.nih.gov/pubmed/35690337
http://dx.doi.org/10.1016/j.jcmgh.2022.06.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9421585/
https://www.ncbi.nlm.nih.gov/pubmed/35690337
http://dx.doi.org/10.1016/j.jcmgh.2022.06.001

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