β-Amyloid–Dependent and –Independent Genetic Pathways Regulating CSF Tau Biomarkers in Alzheimer Disease

BACKGROUND AND OBJECTIVES: Abnormal metabolism of β-amyloid (Aβ) and soluble phosphorylated tau (P-tau), as well as neurodegeneration, are key components of Alzheimer disease (AD), but it is unclear how these different processes are related to genetic risk factors for AD. METHODS: In the Swedish Bio...

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Detalles Bibliográficos
Autores principales: Kumar, Atul, Janelidze, Shorena, Stomrud, Erik, Palmqvist, Sebastian, Hansson, Oskar, Mattsson-Carlgren, Niklas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9421595/
https://www.ncbi.nlm.nih.gov/pubmed/35641311
http://dx.doi.org/10.1212/WNL.0000000000200605

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9421595/
https://www.ncbi.nlm.nih.gov/pubmed/35641311
http://dx.doi.org/10.1212/WNL.0000000000200605

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