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Association of APOE-Independent Alzheimer Disease Polygenic Risk Score With Brain Amyloid Deposition in Asymptomatic Older Adults

BACKGROUND AND OBJECTIVES: Brain amyloid deposition, a major risk factor for Alzheimer disease (AD), is currently estimated by measuring CSF or plasma amyloid peptide levels or by PET imaging. Assessing genetic risks relating to amyloid deposition before any accumulation has occurred would allow for...

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Detalles Bibliográficos
Autores principales: Xicota, Laura, Gyorgy, Beata, Grenier-Boley, Benjamin, Lecoeur, Alexandre, Fontaine, Gaëlle, Danjou, Fabrice, Gonzalez, Jorge Samper, Colliot, Olivier, Amouyel, Philippe, Martin, Garance, Levy, Marcel, Villain, Nicolas, Habert, Marie-Odile, Dubois, Bruno, Lambert, Jean-Charles, Potier, Marie-Claude
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9421597/
https://www.ncbi.nlm.nih.gov/pubmed/35606148
http://dx.doi.org/10.1212/WNL.0000000000200544