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Association of APOE-Independent Alzheimer Disease Polygenic Risk Score With Brain Amyloid Deposition in Asymptomatic Older Adults
BACKGROUND AND OBJECTIVES: Brain amyloid deposition, a major risk factor for Alzheimer disease (AD), is currently estimated by measuring CSF or plasma amyloid peptide levels or by PET imaging. Assessing genetic risks relating to amyloid deposition before any accumulation has occurred would allow for...
Autores principales: | Xicota, Laura, Gyorgy, Beata, Grenier-Boley, Benjamin, Lecoeur, Alexandre, Fontaine, Gaëlle, Danjou, Fabrice, Gonzalez, Jorge Samper, Colliot, Olivier, Amouyel, Philippe, Martin, Garance, Levy, Marcel, Villain, Nicolas, Habert, Marie-Odile, Dubois, Bruno, Lambert, Jean-Charles, Potier, Marie-Claude |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9421597/ https://www.ncbi.nlm.nih.gov/pubmed/35606148 http://dx.doi.org/10.1212/WNL.0000000000200544 |
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