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Design and Validation of the First Family of Photo-Activatable Ligands for Melatonin Receptors

[Image: see text] Melatonin is a neurohormone released in a circadian manner with peak levels at night. Melatonin mediates its effects mainly through G protein-coupled MT(1) and MT(2) receptors. Drugs acting on melatonin receptors are indicated for circadian rhythm- and sleep-related disorders. Tool...

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Detalles Bibliográficos
Autores principales: Somalo-Barranco, Gloria, Serra, Carme, Lyons, David, Piggins, Hugh D., Jockers, Ralf, Llebaria, Amadeu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9421648/
https://www.ncbi.nlm.nih.gov/pubmed/35930058
http://dx.doi.org/10.1021/acs.jmedchem.2c00717