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Design and Validation of the First Family of Photo-Activatable Ligands for Melatonin Receptors
[Image: see text] Melatonin is a neurohormone released in a circadian manner with peak levels at night. Melatonin mediates its effects mainly through G protein-coupled MT(1) and MT(2) receptors. Drugs acting on melatonin receptors are indicated for circadian rhythm- and sleep-related disorders. Tool...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9421648/ https://www.ncbi.nlm.nih.gov/pubmed/35930058 http://dx.doi.org/10.1021/acs.jmedchem.2c00717 |