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Closer to Nature: The Role of MSCs in Recreating the Microenvironment of the Hematopoietic Stem Cell Niche in vitro

BACKGROUND: The stem cell niche in human bone marrow provides scaffolds, cellular frameworks and essential soluble cues to support the stemness of hematopoietic stem and progenitor cells (HSPCs). To decipher this complex structure and the corresponding cellular interactions, a number of in vitro mod...

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Detalles Bibliográficos
Autores principales: Wuchter, Patrick, Diehlmann, Anke, Klüter, Harald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9421702/
https://www.ncbi.nlm.nih.gov/pubmed/36159960
http://dx.doi.org/10.1159/000520932