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siRNA against CD40 delivered via a fungal recognition receptor ameliorates murine acute graft‐versus‐host disease

Acute graft‐versus‐host disease (aGvHD) remains a major threat to a successful outcome after allogeneic hematopoietic stem cell transplantation (HSCT). Although antibody‐based targeting of the CD40/CD40 ligand costimulatory pathway can prevent aGvHD, side effects hampered their clinical application,...

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Detalles Bibliográficos
Autores principales: Heissig, Beate, Salama, Yousef, Tateno, Masatoshi, Takahashi, Satoshi, Hattori, Koichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9421973/
https://www.ncbi.nlm.nih.gov/pubmed/36051085
http://dx.doi.org/10.1002/jha2.439