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Evaluation of vicinity-based hidden Markov models for genotype imputation
BACKGROUND: The decreasing cost of DNA sequencing has led to a great increase in our knowledge about genetic variation. While population-scale projects bring important insight into genotype–phenotype relationships, the cost of performing whole-genome sequencing on large samples is still prohibitive....
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9422108/ https://www.ncbi.nlm.nih.gov/pubmed/36038834 http://dx.doi.org/10.1186/s12859-022-04896-4 |