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Evaluation of vicinity-based hidden Markov models for genotype imputation

BACKGROUND: The decreasing cost of DNA sequencing has led to a great increase in our knowledge about genetic variation. While population-scale projects bring important insight into genotype–phenotype relationships, the cost of performing whole-genome sequencing on large samples is still prohibitive....

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Detalles Bibliográficos
Autores principales: Wang, Su, Kim, Miran, Jiang, Xiaoqian, Harmanci, Arif Ozgun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9422108/
https://www.ncbi.nlm.nih.gov/pubmed/36038834
http://dx.doi.org/10.1186/s12859-022-04896-4