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Membrane transporters control cerebrospinal fluid formation independently of conventional osmosis to modulate intracranial pressure

BACKGROUND: Disturbances in the brain fluid balance can lead to life-threatening elevation in the intracranial pressure (ICP), which represents a vast clinical challenge. Nevertheless, the details underlying the molecular mechanisms governing cerebrospinal fluid (CSF) secretion are largely unresolve...

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Detalles Bibliográficos
Autores principales: Oernbo, Eva K., Steffensen, Annette B., Razzaghi Khamesi, Pooya, Toft-Bertelsen, Trine L., Barbuskaite, Dagne, Vilhardt, Frederik, Gerkau, Niklas J., Tritsaris, Katerina, Simonsen, Anja H., Lolansen, Sara D., Andreassen, Søren N., Hasselbalch, Steen G., Zeuthen, Thomas, Rose, Christine R., Kurtcuoglu, Vartan, MacAulay, Nanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9422132/
https://www.ncbi.nlm.nih.gov/pubmed/36038945
http://dx.doi.org/10.1186/s12987-022-00358-4