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Membrane transporters control cerebrospinal fluid formation independently of conventional osmosis to modulate intracranial pressure
BACKGROUND: Disturbances in the brain fluid balance can lead to life-threatening elevation in the intracranial pressure (ICP), which represents a vast clinical challenge. Nevertheless, the details underlying the molecular mechanisms governing cerebrospinal fluid (CSF) secretion are largely unresolve...
Autores principales: | Oernbo, Eva K., Steffensen, Annette B., Razzaghi Khamesi, Pooya, Toft-Bertelsen, Trine L., Barbuskaite, Dagne, Vilhardt, Frederik, Gerkau, Niklas J., Tritsaris, Katerina, Simonsen, Anja H., Lolansen, Sara D., Andreassen, Søren N., Hasselbalch, Steen G., Zeuthen, Thomas, Rose, Christine R., Kurtcuoglu, Vartan, MacAulay, Nanna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9422132/ https://www.ncbi.nlm.nih.gov/pubmed/36038945 http://dx.doi.org/10.1186/s12987-022-00358-4 |
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