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GM-CSF-mediated inducement of bone marrow MDSCs by TSA and effect on survival of graft in mice

OBJECTIVE: This study analyzed the effect of HDAC inhibitor, trichostatin A (TSA), in inducing granulocyte–macrophage colony-stimulating factor (GM-CSF)-mediated bone marrow (BM) cell differentiation to myeloid-derived suppressor cells (MDSCs) in vitro and in vivo. METHODS: BM cell differentiation t...

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Detalles Bibliográficos
Autores principales: Zhao, Shuguang, Li, Shaohua, Yang, Jingci, Gao, Weinian, Chen, Ziying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9422167/
https://www.ncbi.nlm.nih.gov/pubmed/36031660
http://dx.doi.org/10.1186/s40001-022-00788-8