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GM-CSF-mediated inducement of bone marrow MDSCs by TSA and effect on survival of graft in mice
OBJECTIVE: This study analyzed the effect of HDAC inhibitor, trichostatin A (TSA), in inducing granulocyte–macrophage colony-stimulating factor (GM-CSF)-mediated bone marrow (BM) cell differentiation to myeloid-derived suppressor cells (MDSCs) in vitro and in vivo. METHODS: BM cell differentiation t...
Autores principales: | Zhao, Shuguang, Li, Shaohua, Yang, Jingci, Gao, Weinian, Chen, Ziying |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9422167/ https://www.ncbi.nlm.nih.gov/pubmed/36031660 http://dx.doi.org/10.1186/s40001-022-00788-8 |
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