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Increased PHOSPHO1 expression mediates cortical bone mineral density in renal osteodystrophy

Patients with advanced chronic kidney disease (CKD) often present with skeletal abnormalities, a condition known as renal osteodystrophy (ROD). While tissue non-specific alkaline phosphatase (TNAP) and PHOSPHO1 are critical for bone mineralization, their role in the etiology of ROD is unclear. To ad...

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Detalles Bibliográficos
Autores principales: Hsu, Shun-Neng, Stephen, Louise A, Dillon, Scott, Milne, Elspeth, Javaheri, Behzad, Pitsillides, Andrew A, Novak, Amanda, Millán, Jose Luis, MacRae, Vicky E, Staines, Katherine A, Farquharson, Colin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9422252/
https://www.ncbi.nlm.nih.gov/pubmed/35900032
http://dx.doi.org/10.1530/JOE-22-0097