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The effect of genistein on cisplatin induced ototoxicity and oxidative stress

OBJECTIVE: Cisplatin is an antineoplastic agent used in adults and children for the treatment of various malignant diseases. It can cause irreversible ototoxicity. Genistein is a phytoestrogen. Genistein functions as an antioxidant and cell cycle inhibitor by inhibiting the DNA topoisomerase and tyr...

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Detalles Bibliográficos
Autores principales: Tan, Mehmet, Toplu, Yüksel, Varan, Emrah, Sapmaz, Emrah, Özhan, Onural, Parlakpınar, Hakan, Polat, Alaadin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9422515/
https://www.ncbi.nlm.nih.gov/pubmed/34602350
http://dx.doi.org/10.1016/j.bjorl.2021.07.001