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The effect of genistein on cisplatin induced ototoxicity and oxidative stress
OBJECTIVE: Cisplatin is an antineoplastic agent used in adults and children for the treatment of various malignant diseases. It can cause irreversible ototoxicity. Genistein is a phytoestrogen. Genistein functions as an antioxidant and cell cycle inhibitor by inhibiting the DNA topoisomerase and tyr...
Autores principales: | Tan, Mehmet, Toplu, Yüksel, Varan, Emrah, Sapmaz, Emrah, Özhan, Onural, Parlakpınar, Hakan, Polat, Alaadin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9422515/ https://www.ncbi.nlm.nih.gov/pubmed/34602350 http://dx.doi.org/10.1016/j.bjorl.2021.07.001 |
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