A novel virotherapy encoding human interleukin-7 improves ex vivo T lymphocyte functions in immunosuppressed patients with septic shock and critically ill COVID-19

A majority of patients with sepsis surviving the first days in intensive care units (ICU) enter a state of immunosuppression contributing to their worsening. A novel virotherapy based on the non-propagative Modified Virus Ankara (MVA) expressing the human interleukin-7 (hIL-7) cytokine fused to an F...

Descripción completa

Detalles Bibliográficos
Autores principales: Crausaz, Morgane, Monneret, Guillaume, Conti, Filippo, Lukaszewicz, Anne-Claire, Marchand, Jean-Baptiste, Martin, Perrine, Inchauspé, Geneviève, Venet, Fabienne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9422896/
https://www.ncbi.nlm.nih.gov/pubmed/36045686
http://dx.doi.org/10.3389/fimmu.2022.939899

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9422896/
https://www.ncbi.nlm.nih.gov/pubmed/36045686
http://dx.doi.org/10.3389/fimmu.2022.939899

Ejemplares similares