Flexible Target Recognition of the Intrinsically Disordered DNA-Binding Domain of CytR Monitored by Single-Molecule Fluorescence Spectroscopy

[Image: see text] The intrinsically disordered DNA-binding domain of cytidine repressor (CytR-DBD) folds in the presence of target DNA and regulates the expression of multiple genes in E. coli. To explore the conformational rearrangements in the unbound state and the target recognition mechanisms of...

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Detalles Bibliográficos
Autores principales: Mitra, Shrutarshi, Oikawa, Hiroyuki, Rajendran, Divya, Kowada, Toshiyuki, Mizukami, Shin, Naganathan, Athi N., Takahashi, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9422980/
https://www.ncbi.nlm.nih.gov/pubmed/35969476
http://dx.doi.org/10.1021/acs.jpcb.2c02791

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9422980/
https://www.ncbi.nlm.nih.gov/pubmed/35969476
http://dx.doi.org/10.1021/acs.jpcb.2c02791

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