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SARS-CoV-2 Delta variant induces enhanced pathology and inflammatory responses in K18-hACE2 mice

The COVID-19 pandemic has been fueled by SARS-CoV-2 novel variants of concern (VOC) that have increased transmissibility, receptor binding affinity, and other properties that enhance disease. The goal of this study is to characterize unique pathogenesis of the Delta VOC strain in the K18-hACE2-mouse...

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Detalles Bibliográficos
Autores principales: Lee, Katherine S., Wong, Ting Y., Russ, Brynnan P., Horspool, Alexander M., Miller, Olivia A., Rader, Nathaniel A., Givi, Jerome P., Winters, Michael T., Wong, Zeriel Y. A., Cyphert, Holly A., Denvir, James, Stoilov, Peter, Barbier, Mariette, Roan, Nadia R., Amin, Md. Shahrier, Martinez, Ivan, Bevere, Justin R., Damron, F. Heath
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9423646/
https://www.ncbi.nlm.nih.gov/pubmed/36037222
http://dx.doi.org/10.1371/journal.pone.0273430