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SARS-CoV-2 Delta variant induces enhanced pathology and inflammatory responses in K18-hACE2 mice
The COVID-19 pandemic has been fueled by SARS-CoV-2 novel variants of concern (VOC) that have increased transmissibility, receptor binding affinity, and other properties that enhance disease. The goal of this study is to characterize unique pathogenesis of the Delta VOC strain in the K18-hACE2-mouse...
Autores principales: | Lee, Katherine S., Wong, Ting Y., Russ, Brynnan P., Horspool, Alexander M., Miller, Olivia A., Rader, Nathaniel A., Givi, Jerome P., Winters, Michael T., Wong, Zeriel Y. A., Cyphert, Holly A., Denvir, James, Stoilov, Peter, Barbier, Mariette, Roan, Nadia R., Amin, Md. Shahrier, Martinez, Ivan, Bevere, Justin R., Damron, F. Heath |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9423646/ https://www.ncbi.nlm.nih.gov/pubmed/36037222 http://dx.doi.org/10.1371/journal.pone.0273430 |
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