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IRE1α overexpression in malignant cells limits tumor progression by inducing an anti-cancer immune response

IRE1α is one of the three ER transmembrane transducers of the Unfolded Protein Response (UPR) activated under endoplasmic reticulum (ER) stress. IRE1α activation has a dual role in cancer as it may be either pro- or anti-tumoral depending on the studied models. Here, we describe the discovery that e...

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Detalles Bibliográficos
Autores principales: Martinez-Turtos, Adriana, Paul, Rachel, Grima-Reyes, Manuel, Issaoui, Hussein, Krug, Adrien, Mhaidly, Rana, Bossowski, Jozef P., Chiche, Johanna, Marchetti, Sandrine, Verhoeyen, Els, Chevet, Eric, Ricci, Jean-Ehrland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9423862/
https://www.ncbi.nlm.nih.gov/pubmed/36046811
http://dx.doi.org/10.1080/2162402X.2022.2116844