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Analysis of transcriptomic responses to SARS-CoV-2 reveals plausible defective pathways responsible for increased susceptibility to infection and complications and helps to develop fast-track repositioning of drugs against COVID-19

BACKGROUND: To understand the transcriptomic response to SARS-CoV-2 infection, is of the utmost importance to design diagnostic tools predicting the severity of the infection. METHODS: We have performed a deep sampling analysis of the viral transcriptomic data oriented towards drug repositioning. Us...

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Detalles Bibliográficos
Autores principales: deAndrés-Galiana, Enrique J., Fernández-Martínez, Juan Luis, Álvarez-Machancoses, Óscar, Bea, Guillermina, Galmarini, Carlos M., Kloczkowski, Andrzej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9423878/
https://www.ncbi.nlm.nih.gov/pubmed/36067633
http://dx.doi.org/10.1016/j.compbiomed.2022.106029