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Discovery and characterization of tumor antigens in hepatocellular carcinoma for mRNA vaccine development

BACKGROUND: mRNA vaccines are emerging as new targets for cancer immunotherapy. However, the potential tumor antigens for mRNA vaccine design in hepatocellular carcinoma (HCC) remain to be elucidated. METHODS: Genetic and RNA-Seq data were obtained from TCGA and ICGC. Tumor-specific antigens (TSAs)...

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Detalles Bibliográficos
Autores principales: Fu, Jiantao, Chen, Feng, Lin, Yuanji, Gao, Jin, Chen, Anna, Yang, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9423891/
https://www.ncbi.nlm.nih.gov/pubmed/36038676
http://dx.doi.org/10.1007/s00432-022-04325-2