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Hepatoprotection of Paederia scandens (Lour.) Merr. on Acetaminophen-Related Hepatic Injury Rats by (1)H-NMR-Based Metabonomics Coupled with Network Pharmacology

BACKGROUND: Acetaminophen-related hepatic injury (ARHI) is a kind of acute hepatic injury caused by overdosing acetaminophen, which is mainly related to toxic metabolite production, oxidative stress, and mitochondrial dysfunction. The extract of Paederia scandens (Lour.) Merr. (PSM) has the abilitie...

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Detalles Bibliográficos
Autores principales: Tang, Chao-Ling, Ma, Ning, Sun, Wan-Ying, Wang, Wei, Zhu, Li-Peng, Wang, Rui-Qi, Liu, Jie-Yan, Zhang, Xiao-Po
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9423956/
https://www.ncbi.nlm.nih.gov/pubmed/36045664
http://dx.doi.org/10.1155/2022/1375864