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Distinct mutational features across preinvasive and invasive subtypes identified through comprehensive profiling of surgically resected lung adenocarcinoma

Lung adenocarcinoma (LUAD) is a heterogeneous disease. Our study aimed to understand the unique molecular features of preinvasive to invasive LUAD subtypes. We retrospectively analyzed the clinical, histopathological, and molecular data of 3,254 Chinese patients with preinvasive lesions (n = 252), m...

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Detalles Bibliográficos
Autores principales: Xiang, Chan, Ji, Chunyu, Cai, Yiran, Teng, Haohua, Wang, Yulu, Zhao, Ruiying, Shang, Zhanxian, Guo, Lianying, Chen, Shengnan, Lizaso, Analyn, Lin, Jing, Wang, Haozhe, Li, Bing, Zhang, Zhou, Zhao, Jikai, Wei, Jinzhi, Liu, Jiaxin, Zhu, Lei, Fang, Wentao, Han, Yuchen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9424111/
https://www.ncbi.nlm.nih.gov/pubmed/35641658
http://dx.doi.org/10.1038/s41379-022-01076-w