Cargando…

Acid sphingomyelinase deactivation post-ischemia promotes brain angiogenesis and remodeling by small extracellular vesicles

Antidepressants have been reported to enhance stroke recovery independent of the presence of depressive symptoms. They have recently been proposed to exert their mood-stabilizing actions by inhibition of acid sphingomyelinase (ASM), which catalyzes the hydrolysis of sphingomyelin to ceramide. Their...

Descripción completa

Detalles Bibliográficos
Autores principales: Mohamud Yusuf, Ayan, Hagemann, Nina, Zhang, Xiaoni, Zafar, Maria, Hussner, Tanja, Bromkamp, Carolin, Martiny, Carlotta, Tertel, Tobias, Börger, Verena, Schumacher, Fabian, Solari, Fiorella A., Hasenberg, Mike, Kleinschnitz, Christoph, Doeppner, Thorsten R., Kleuser, Burkhard, Sickmann, Albert, Gunzer, Matthias, Giebel, Bernd, Kolesnick, Richard, Gulbins, Erich, Hermann, Dirk M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9424180/
https://www.ncbi.nlm.nih.gov/pubmed/36038749
http://dx.doi.org/10.1007/s00395-022-00950-7