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Regulation of CCL2 by EZH2 affects tumor-associated macrophages polarization and infiltration in breast cancer

Tumor associated macrophages (TAMs) play an important role in tumorigenesis, development and anti-cancer drug therapy. However, very few epigenetic compounds have been elucidated to affect tumor growth by educating TAMs in the tumor microenvironment (TME). Herein, we identified that EZH2 performs a...

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Detalles Bibliográficos
Autores principales: Wang, Ya-fang, Yu, Lei, Hu, Zong-long, Fang, Yan-fen, Shen, Yan-yan, Song, Min-fang, Chen, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9424193/
https://www.ncbi.nlm.nih.gov/pubmed/36038549
http://dx.doi.org/10.1038/s41419-022-05169-x