Anti-Tumor Effect of IDF-11774, an Inhibitor of Hypoxia-Inducible Factor-1, on Melanoma

Melanoma is one of the most aggressive skin cancers. Hypoxia contributes to the aggressiveness of melanoma by promoting cancer growth and metastasis. Upregulation of cyclin D1 can promote uncontrolled cell proliferation in melanoma, whereas stimulation of cytotoxic T cell activity can inhibit it. Ep...

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Detalles Bibliográficos
Autores principales: Kim, Nan-Hyung, Jeong, Jong Heon, Park, Yu Jeong, Shin, Hui Young, Choi, Woo Kyoung, Lee, Kyeong, Lee, Ai-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9424330/
https://www.ncbi.nlm.nih.gov/pubmed/35712870
http://dx.doi.org/10.4062/biomolther.2022.061

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9424330/
https://www.ncbi.nlm.nih.gov/pubmed/35712870
http://dx.doi.org/10.4062/biomolther.2022.061

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