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Anti-Tumor Effect of IDF-11774, an Inhibitor of Hypoxia-Inducible Factor-1, on Melanoma
Melanoma is one of the most aggressive skin cancers. Hypoxia contributes to the aggressiveness of melanoma by promoting cancer growth and metastasis. Upregulation of cyclin D1 can promote uncontrolled cell proliferation in melanoma, whereas stimulation of cytotoxic T cell activity can inhibit it. Ep...
Autores principales: | Kim, Nan-Hyung, Jeong, Jong Heon, Park, Yu Jeong, Shin, Hui Young, Choi, Woo Kyoung, Lee, Kyeong, Lee, Ai-Young |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Society of Applied Pharmacology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9424330/ https://www.ncbi.nlm.nih.gov/pubmed/35712870 http://dx.doi.org/10.4062/biomolther.2022.061 |
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