Efonidipine Inhibits JNK and NF-κB Pathway to Attenuate Inflammation and Cell Migration Induced by Lipopolysaccharide in Microglial Cells

Efonidipine, a calcium channel blocker, is widely used for the treatment of hypertension and cardiovascular diseases. In our preliminary study using structure-based virtual screening, efonidipine was identified as a potential inhibitor of c-Jun N-terminal kinase 3 (JNK3). Although its antihypertensi...

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Detalles Bibliográficos
Autores principales: Nguyen, Ngoc Minh, Duong, Men Thi Hoai, Nguyen, Phuong Linh, Bui, Bich Phuong, Ahn, Hee-Chul, Cho, Jungsook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9424335/
https://www.ncbi.nlm.nih.gov/pubmed/35993250
http://dx.doi.org/10.4062/biomolther.2022.076

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9424335/
https://www.ncbi.nlm.nih.gov/pubmed/35993250
http://dx.doi.org/10.4062/biomolther.2022.076

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