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Hyperactivation of Wnt/β-catenin and Jak/Stat3 pathways in human and zebrafish foetal growth restriction models: Implications for pharmacological rescue

Foetal Growth Restriction (FGR), previously known as Intrauterine Growth Restriction (IUGR), is an obstetrical condition due to placental insufficiency, affecting yearly about 30 million newborns worldwide. In this work, we aimed to identify and pharmacologically target signalling pathways specifica...

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Detalles Bibliográficos
Autores principales: Risato, Giovanni, Celeghin, Rudy, Brañas Casas, Raquel, Dinarello, Alberto, Zuppardo, Alessandro, Vettori, Andrea, Pilichou, Kalliopi, Thiene, Gaetano, Basso, Cristina, Argenton, Francesco, Visentin, Silvia, Cosmi, Erich, Tiso, Natascia, Beffagna, Giorgia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9424487/
https://www.ncbi.nlm.nih.gov/pubmed/36051436
http://dx.doi.org/10.3389/fcell.2022.943127