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Dissecting the dynamic transcriptional landscape of early T helper cell differentiation into Th1, Th2, and Th1/2 hybrid cells

Selective differentiation of CD4+ T helper (Th) cells into specialized subsets such as Th1 and Th2 cells is a key element of the adaptive immune system driving appropriate immune responses. Besides those canonical Th-cell lineages, hybrid phenotypes such as Th1/2 cells arise in vivo, and their gener...

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Detalles Bibliográficos
Autores principales: Burt, Philipp, Peine, Michael, Peine, Caroline, Borek, Zuzanna, Serve, Sebastian, Floßdorf, Michael, Hegazy, Ahmed N., Höfer, Thomas, Löhning, Max, Thurley, Kevin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9424495/
https://www.ncbi.nlm.nih.gov/pubmed/36052070
http://dx.doi.org/10.3389/fimmu.2022.928018