Cargando…

Cyclophilin A contributes to shikonin-induced glioma cell necroptosis and promotion of chromatinolysis

Shikonin induces glioma cell death via necroptosis, a caspase-independent programmed cell death pathway that is chiefly regulated by receptor-interacting serine/threonine protein kinase1 (RIP1) and 3 (RIP3). Chromatinolysis is considered as one of the key events leading to cell death during necropto...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Xinyu, Fan, Liwen, Wang, Xuanzhong, Luo, Tianfei, Liu, Linlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9424531/
https://www.ncbi.nlm.nih.gov/pubmed/36038617
http://dx.doi.org/10.1038/s41598-022-19066-y