Developing methods to study conformational changes in RNA crystals using a photocaged ligand

Crystallographic observation of structural changes in real time requires that those changes be uniform both spatially and temporally. A primary challenge with time-resolved ligand-mixing diffraction experiments is asynchrony caused by variable factors, such as efficiency of mixing, rate of diffusion...

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Detalles Bibliográficos
Autores principales: Lee, Hyun Kyung, Conrad, Chelsie E., Magidson, Valentin, Heinz, William F., Pauly, Gary, Yu, Ping, Ramakrishnan, Saminathan, Stagno, Jason R., Wang, Yun-Xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9424638/
https://www.ncbi.nlm.nih.gov/pubmed/36052167
http://dx.doi.org/10.3389/fmolb.2022.964595

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9424638/
https://www.ncbi.nlm.nih.gov/pubmed/36052167
http://dx.doi.org/10.3389/fmolb.2022.964595

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